The first clinical application of gene therap | vedclass

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(D) The first clinical gene therapy was given in $1990$ to a $4$-year-old girl with Adenosine Deaminase $(ADA)$ deficiency.$ADA$ enzyme is crucial for

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Adenosine deaminase deficiency

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(D) The first clinical gene therapy was given in $1990$ to a $4$-year-old girl with Adenosine Deaminase $(ADA)$ deficiency.$ADA$ enzyme is crucial for the immune system to function.This deficiency leads to Severe Combined Immunodeficiency $(SCID)$.In this therapy,lymphocytes from the patient's blood were grown in a culture outside the body,and a functional $ADA$ $cDNA$ was introduced into these lymphocytes using a retroviral vector,which were then returned to the patient.

The first clinical application of gene therapy was used in $1990$ on a four-year-old girl for:

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