When E_2 competition is not a concern,which o | vedclass

Name: Exam Paper Generator | JEE NEET Paper Generator | Vedclass
Brand: Vedclass
Rating: 5 (35 reviews)

Question

(D) In an $S_N2$ reaction,the rate depends on the strength of the nucleophile. $A$ stronger nucleophile is typically a stronger base,provided the ster

Vedclass · Accepted Answer

$OH^-$

Vedclass · Answer

(D) In an $S_N2$ reaction,the rate depends on the strength of the nucleophile. $A$ stronger nucleophile is typically a stronger base,provided the steric hindrance is not significant. Comparing the given nucleophiles: $1$. $H_2O$ is a neutral molecule and a weak nucleophile. $2$. $Cl^-$ is a weak nucleophile in polar protic solvents due to solvation. $3$. $HCOO^-$ (formate ion) has resonance stabilization,which reduces the availability of the lone pair,making it a weaker nucleophile compared to $OH^-$. $4$. $OH^-$ is a strong,small,and highly reactive nucleophile. Therefore,$OH^-$ is the best nucleophile among the given options for an $S_N2$ reaction when $E_2$ competition is ignored.

When $E_2$ competition is not a concern,which of the following is the best nucleophile for an $S_N2$ reaction?

Similar Questions

Identify compound $Y$ in the following reaction.
$C_2H_5Cl + Y \xrightarrow{\Delta} C_2H_5CN$

The following reaction,$(CH_3)_3CBr + H_2O \rightarrow (CH_3)_3COH + HBr$,is an example of:

Tertiary alkyl halides are practically inert to substitution by the $S_N2$ mechanism due to:

$A$ mixture of two organic compounds is treated with sodium metal in an ether solvent to produce isobutane. What are these two chloro compounds?

Conversion of $I$ to $II$:

Vedclass Test Series

Exam Paper Generator

Online Exam Module