Write the reaction for the nitration of anisole.
(N/A) Nitration of anisole is an electrophilic aromatic substitution reaction. Anisole reacts with a mixture of concentrated sulfuric acid $(H_2SO_4)$ and concentrated nitric acid $(HNO_3)$ to yield a mixture of ortho-nitroanisole and para-nitroanisole.
The reaction is as follows:
$C_6H_5OCH_3 + HNO_3 \xrightarrow{H_2SO_4} C_6H_4(NO_2)OCH_3$ (ortho and para isomers).
The $-OCH_3$ group is ortho and para directing,and it activates the benzene ring towards electrophilic substitution.
The reaction is as follows:
$C_6H_5OCH_3 + HNO_3 \xrightarrow{H_2SO_4} C_6H_4(NO_2)OCH_3$ (ortho and para isomers).
The $-OCH_3$ group is ortho and para directing,and it activates the benzene ring towards electrophilic substitution.
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