Which of the following treatments cannot comp | vedclass

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Question

(A) $ADA$ deficiency (Adenosine Deaminase deficiency) is a genetic disorder caused by the deletion of the gene for adenosine deaminase. $1$. Enzyme re

Vedclass · Accepted Answer

Enzyme replacement therapy

Vedclass · Answer

(A) $ADA$ deficiency (Adenosine Deaminase deficiency) is a genetic disorder caused by the deletion of the gene for adenosine deaminase. $1$. Enzyme replacement therapy involves the periodic injection of functional $ADA$ into the patient. It does not provide a permanent cure because the patient's own cells do not produce the enzyme. $2$. Bone marrow transplantation can be curative if performed early,but it is not always successful due to the difficulty in finding a suitable donor. $3$. Gene therapy is considered a potential permanent cure because it involves introducing functional $ADA$ cDNA into the patient's lymphocytes,which are then cultured and returned to the patient. Since enzyme replacement therapy requires repeated administration and is not a permanent cure,it is the primary answer in this context.

Column-$I$	Column-$II$
$(1)$ Diabetes	$(a)$ $ADA$
$(2)$ Enzyme replacement therapy	$(b)$ Alpha-lactalbumin
$(3)$ Emphysema	$(c)$ Insulin
$(4)$ Rosie cow	$(d)$ $\alpha-1$-Antitrypsin
	$(e)$ Typhoid

Which of the following treatments cannot completely cure $ADA$ deficiency?

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Match the columns:

Column-$I$ Column-$II$

$(1)$ Diabetes $(a)$ $ADA$

$(2)$ Enzyme replacement therapy $(b)$ Alpha-lactalbumin

$(3)$ Emphysema $(c)$ Insulin

$(4)$ Rosie cow $(d)$ $\alpha-1$-Antitrypsin

$(e)$ Typhoid

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