Why are genetically engineered lymphocytes pe | vedclass

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Question

(D) In the treatment of $ADA$ (Adenosine Deaminase) deficiency,lymphocytes are extracted from the patient's blood and a functional $ADA$ gene is intro

Vedclass · Accepted Answer

$A$ and $C$

Vedclass · Answer

(D) In the treatment of $ADA$ (Adenosine Deaminase) deficiency,lymphocytes are extracted from the patient's blood and a functional $ADA$ gene is introduced into them. These genetically engineered cells are not immortal and have a limited lifespan. Furthermore,over time,the introduced gene may be lost from these cells or the cells may die. Therefore,to provide continuous treatment,these genetically engineered lymphocytes must be periodically reintroduced into the patient's body. Thus,the correct option is $D$.

Why are genetically engineered lymphocytes periodically introduced into the patient in the treatment of $ADA$ deficiency?

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