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(C) $Km$ is the Michaelis-Menten constant. It represents the substrate concentration at which the rate of an enzyme-catalyzed reaction is half of its

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$ES$ complex

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(C) $Km$ is the Michaelis-Menten constant. It represents the substrate concentration at which the rate of an enzyme-catalyzed reaction is half of its maximum velocity $(V_{max})$. This constant is a measure of the affinity of an enzyme for its substrate and is fundamentally associated with the formation and dissociation of the enzyme-substrate $(ES)$ complex.

$Km$ is related to

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