Which of the following statements is correct regarding enzyme inhibition?

• A
  Non-competitive inhibition of an enzyme can be overcome by adding a large amount of substrate.
• B
  Competitive inhibition occurs when the inhibitor competes with the enzyme to bind to the substrate protein.
• C
  Competitive inhibition occurs when the substrate and the inhibitor compete to bind to the active site of the enzyme.
• D
  Non-competitive inhibitors bind to the active site of the enzyme.