The non-protein part of enzymes is known as:

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(D) Enzymes are composed of one or several polypeptide chains. However,there are a number of cases in which non-protein constituents called co-factors

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All of the above

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(D) Enzymes are composed of one or several polypeptide chains. However,there are a number of cases in which non-protein constituents called co-factors are bound to the apoenzyme to make the enzyme catalytically active.Co-factors are of three kinds: $1$. Prosthetic groups: These are organic compounds and are distinguished from other co-factors in that they are tightly bound to the apoenzyme.$2$. Co-enzymes: These are also organic compounds but their association with the apoenzyme is only transient,usually occurring during the course of catalysis.$3$. Metal ions: $A$ number of enzymes require metal ions for their activity which form coordination bonds with side chains at the active site.Since prosthetic groups,co-enzymes,and metal ions are all types of non-protein constituents that assist enzyme activity,they are collectively referred to as co-factors.

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