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(D) The binding of oxygen with hemoglobin is primarily a function of the partial pressure of oxygen $(pO_2)$.However,other factors such as the partial

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(D) The binding of oxygen with hemoglobin is primarily a function of the partial pressure of oxygen $(pO_2)$.However,other factors such as the partial pressure of carbon dioxide $(pCO_2)$,hydrogen ion concentration $(pH)$,and temperature also interfere with this binding.An increase in $pCO_2$,a decrease in $pH$ (higher acidity),and an increase in temperature shift the oxygen-hemoglobin dissociation curve to the right,facilitating the dissociation of oxygen from hemoglobin.Therefore,all the listed factors affect the binding of oxygen with hemoglobin.

Which of the following factors affect the binding of oxygen with hemoglobin?

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