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(A) The maintenance of high osmolarity in the medullary interstitial fluid is primarily achieved by the counter-current mechanism.This mechanism invol

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Loop of Henle

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(A) The maintenance of high osmolarity in the medullary interstitial fluid is primarily achieved by the counter-current mechanism.This mechanism involves the Loop of Henle and the vasa recta.The descending limb of the Loop of Henle is permeable to water but nearly impermeable to electrolytes,while the ascending limb is impermeable to water but allows transport of electrolytes.This differential permeability creates a concentration gradient in the medullary interstitium,which is essential for the concentration of urine.

Which of the following plays a significant role in maintaining the high osmolarity of the medullary interstitial fluid?

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