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(B) Sickle-cell anemia is caused by a point mutation in the $\beta$-globin chain of hemoglobin,where glutamic acid is replaced by valine at the $6^{th

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Different mobility

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(B) Sickle-cell anemia is caused by a point mutation in the $\beta$-globin chain of hemoglobin,where glutamic acid is replaced by valine at the $6^{th}$ position. This substitution changes the electrical charge of the hemoglobin molecule. Because electrophoresis separates molecules based on their charge-to-mass ratio,normal hemoglobin $(HbA)$ and sickle-cell hemoglobin $(HbS)$ exhibit different electrophoretic mobilities. Therefore,they will show different mobility in an electrophoretic field.

When the blood hemoglobin of a normal person and a sickle-cell patient is placed in an electrophoretic field,what will be observed?

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