If the secretion of parietal cells of the gas | vedclass

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Question

(A) The parietal cells (also known as oxyntic cells) of the gastric glands are responsible for the secretion of $HCl$ (hydrochloric acid) and Castle's

Vedclass · Accepted Answer

In the absence of $HCl$,inactive pepsinogen will not be converted into the active enzyme pepsin.

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(A) The parietal cells (also known as oxyntic cells) of the gastric glands are responsible for the secretion of $HCl$ (hydrochloric acid) and Castle's intrinsic factor.$HCl$ plays a crucial role in the activation of the proenzyme pepsinogen into its active form,pepsin,by providing an acidic $pH$ (approximately $1.8$).If the secretion of $HCl$ is blocked by an inhibitor,the conversion of inactive pepsinogen to active pepsin will not occur.Therefore,the digestion of proteins in the stomach will be severely affected.

If the secretion of parietal cells of the gastric glands is blocked by an inhibitor,what will happen?

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