Vitamin K is required for: | vedclass

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(B) Vitamin $K$ is essential for the synthesis of several clotting factors in the liver,including prothrombin (Factor $II$),Factor $VII$,Factor $IX$,a

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Synthesis of prothrombin

Vedclass · Answer

(B) Vitamin $K$ is essential for the synthesis of several clotting factors in the liver,including prothrombin (Factor $II$),Factor $VII$,Factor $IX$,and Factor $X$.Specifically,it acts as a cofactor for the enzyme gamma-glutamyl carboxylase,which carboxylates glutamic acid residues on these clotting factors,enabling them to bind calcium ions and participate in the blood coagulation cascade.Therefore,the synthesis of prothrombin in the liver is dependent on Vitamin $K$.

Vitamin $K$ is required for:

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