Which structure of protein is controlled by genes?

Given below are two statements.
Statement $I$ - Most of the blood proteins are acidic proteins.
Statement $II$ - Derived proteins are not found in nature.
In the light of above statements,select the correct option given below:

$S$ - Statement: The amino acid with a non-polar $R$ group is serine.
$R$ - Reason: The amino acid with a polar and uncharged $R$ group is threonine.

Simple proteins bonded with a non-proteinic prosthetic group (acting as cofactor) are called:

Which of the following groups in the structure of an amino acid is acidic?

Amino acids not synthesized in the body are called