(C) According to Chargaff's rule, in a double-stranded $DNA$ molecule, the amount of purine bases $(Adenine + Guanine)$ is always equal to the amount

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(C) According to Chargaff's rule, in a double-stranded $DNA$ molecule, the amount of purine bases $(Adenine + Guanine)$ is always equal to the amount of pyrimidine bases $(Thymine + Cytosine)$.Therefore, the ratio of purines to pyrimidines is $1:1$, which means they are present in an equal ratio.