What is the absolute configuration of the giv | vedclass

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(B) To determine the absolute configuration,we assign priorities to the groups attached to each chiral center using Cahn-Ingold-Prelog $(CIP)$ rules.F

Vedclass · Accepted Answer

$R, R$

Vedclass · Answer

(B) To determine the absolute configuration,we assign priorities to the groups attached to each chiral center using Cahn-Ingold-Prelog $(CIP)$ rules.For the left chiral carbon: The priorities are $1: -OH$,$2: -COOH$,$3: -CH(OH)COOH$,$4: -H$.Since the lowest priority group $(-H)$ is on a dashed bond,we trace $1$ $\rightarrow 2$ $\rightarrow 3$. The direction is clockwise,so the configuration is $R$.For the right chiral carbon: The priorities are $1: -OH$,$2: -COOH$,$3: -CH(OH)COOH$,$4: -H$.Since the lowest priority group $(-H)$ is on a wedged bond,we trace $1$ $\rightarrow 2$ $\rightarrow 3$. The direction is counter-clockwise,which would be $S$,but since the lowest priority group is on a wedge,we reverse it to $R$.Thus,the configuration is $R, R$.

What is the absolute configuration of the given molecule?

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