Osteoporosis,an age-related disorder of the skeletal system,is characterized by:

  • A
    Decreased levels of estrogen.
  • B
    Inflammation of joints due to accumulation of uric acid.
  • C
    Immune system disorder affecting the neuromuscular junction.
  • D
    High levels of calcium and sodium.

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$A$: Inflammation of a skeletal joint may immobilize the movements of the joint.
$R$: Uric acid crystals in the joint cavity and ossification of articular cartilage lead to this.

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