Name the ions responsible for unmasking the a | vedclass

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(C) During muscle contraction,the signal for contraction is sent by the central nervous system via a motor neuron. When the action potential reaches t

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Calcium

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(C) During muscle contraction,the signal for contraction is sent by the central nervous system via a motor neuron. When the action potential reaches the neuromuscular junction,it triggers the release of neurotransmitters,leading to an action potential in the sarcolemma. This action potential spreads through the $T$-tubules and triggers the release of $Ca^{2+}$ ions from the sarcoplasmic reticulum into the sarcoplasm. These $Ca^{2+}$ ions bind to the troponin subunit on the actin filaments. This binding causes a conformational change that moves tropomyosin away from the active sites on the actin filament,thereby 'unmasking' them. Once the active sites are exposed,the myosin heads can bind to them to form cross-bridges,initiating the contraction process. Therefore,$Ca^{2+}$ ions are responsible for this process.

Name the ions responsible for unmasking the active sites on myosin for cross-bridge formation during muscle contraction.

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