A fall in glomerular filtration rate (GFR) ac | vedclass

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(A) : The amount of the filtrate formed by the kidneys per minute is called glomerular filtration rate $(GFR)$. $GFR$ in a healthy individual is appro

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juxtaglomerular cells to release renin

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(A) : The amount of the filtrate formed by the kidneys per minute is called glomerular filtration rate $(GFR)$. $GFR$ in a healthy individual is approximately $125 	ext{ ml/minute}$, $i.e.$, $180 	ext{ litres}$ per day.The kidneys have built-in mechanisms for the regulation of $GFR$. One such efficient mechanism is carried out by the juxtaglomerular apparatus $(JGA)$.$JGA$ is a special sensitive region formed by cellular modifications in the distal convoluted tubule $(DCT)$ and the afferent arteriole at the location of their contact.$A$ fall in $GFR$ activates the $JG$ cells to release renin, which converts angiotensinogen in the blood to angiotensin $I$ and further to angiotensin $II$. Angiotensin $II$ is a powerful vasoconstrictor that increases the glomerular blood pressure and thereby brings the $GFR$ back to normal.

$A$ fall in glomerular filtration rate $(GFR)$ activates

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