Active transport differs from passive transport in that active transport

$S -$ Statement: Energy is consumed during active transport.
$R -$ Reason: This transport occurs against the concentration gradient of the substances.

What is the main difference between active and passive transport?

Which of the following does not require carrier molecules during transport through cell membranes?

Consider the following statements and choose the correct answer:
$I.$ Carrier proteins are needed by both facilitated diffusion and active transport and are sensitive to inhibitors that react with protein side chains.
$II.$ Different types of proteins present in the membrane play a major role in both active as well as passive transport.
$III.$ The carrier proteins needed by facilitated and active transport are specific.
$IV.$ There is no need of energy to pump molecules against a concentration gradient in active transport.
$V.$ Transport rate reaches a saturation point when all the active proteins are used.

Active transport of ions by the cell requires