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(D) The susceptibility of a carbonyl group to nucleophilic attack depends on the electrophilicity of the carbonyl carbon. This electrophilicity is inc

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$CH_3COCl$

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(D) The susceptibility of a carbonyl group to nucleophilic attack depends on the electrophilicity of the carbonyl carbon. This electrophilicity is increased by the presence of an electron-withdrawing group attached to the carbonyl carbon. Among the given derivatives,the chloride ion $(Cl^-)$ is the weakest base and therefore the best leaving group. Since $Cl$ is highly electronegative and a good leaving group,it exerts a strong inductive effect,making the carbonyl carbon in $CH_3COCl$ the most electron-deficient and thus the most susceptible to nucleophilic attack.

Among the given compounds,the most susceptible to nucleophilic attack at the carbonyl group is

Similar Questions

Identify the product $B$ in the following series of reaction.
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In the following reaction sequence,identify product $Q$ and reagent $R$:

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The increasing order of acidic strength among the following compounds is
$I.$ Benzoic acid
$II.$ $4-$nitrobenzoic acid
$III.$ $3, 4-$dinitrobenzoic acid
$IV.$ $4-$methoxybenzoic acid

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