Assertion: Haemophilia is a recessive sex-lin | vedclass

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(C) Haemophilia,also known as bleeder's disease,is a classic example of recessive sex-linked inheritance in humans.It is masked in the heterozygous co

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If the Assertion is correct but Reason is incorrect.

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(C) Haemophilia,also known as bleeder's disease,is a classic example of recessive sex-linked inheritance in humans.It is masked in the heterozygous condition.The person suffering from this disease lacks clotting factors $VIII$ and $IX$,which are essential for blood coagulation.$A$ small cut may lead to continuous bleeding.Men are primarily affected by this disease,while women typically act as carriers.The mutation of a structural gene on chromosome number $15$ is associated with Marfan syndrome,not haemophilia.Marfan syndrome results in the formation of abnormal connective tissues and extreme looseness of joints.Therefore,the Assertion is correct,but the Reason is incorrect.

Assertion: Haemophilia is a recessive sex-linked disease.
Reason: Haemophilia occurs due to mutation of a structural gene on chromosome $15$.

Similar Questions

In sickle-cell anaemia,which of the following amino acids is substituted?

In the $\beta$-globin chain of haemoglobin of an individual,if the sixth amino acid,Glutamic acid (Glu),is replaced by Valine (Val),then the individual will be suffering from:

In Huntington's disease,the unaffected persons are homozygous for normal allele $h$. The following pedigree is erroneous because:

$A$: The heterozygotic female for haemophilia may transmit the disease to sons.
$R$: Such traits show criss-cross inheritance.

Which genotype is responsible for the carrier state of sickle-cell anemia?

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Assertion: Haemophilia is a recessive sex-linked disease.Reason: Haemophilia occurs due to mutation of a structural gene on chromosome $15$.