Assertion : Mast cells in the human body rele | vedclass

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(A) Mast cells contain granules rich in histamine,serotonin,and heparin. When allergens enter the body,they bind to $IgE$ antibodies on the surface of

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If both Assertion and Reason are correct and the Reason is a correct explanation of the Assertion.

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(A) Mast cells contain granules rich in histamine,serotonin,and heparin. When allergens enter the body,they bind to $IgE$ antibodies on the surface of mast cells in sensitive individuals. This binding triggers the degranulation of mast cells,causing them to release large amounts of inflammatory chemicals like histamine into the bloodstream. Histamine acts as an initiator of the inflammatory response,leading to symptoms such as capillary dilation,increased permeability,mucus secretion,and swelling,which are characteristic of allergic reactions. Therefore,the Reason correctly explains why mast cells release these chemicals.

Assertion : Mast cells in the human body release excessive amounts of inflammatory chemicals,which cause allergic reactions.
Reason : Allergens in the environment on reaching human body stimulate mast cells in certain individuals.

Similar Questions

Which substances are responsible for allergies?
$(i)$ Histamine $(ii)$ Serotonin $(iii)$ Adrenaline $(iv)$ Heparin

Which drugs are responsible for the relief of allergies?

The type of antibodies produced during the allergic reaction is:

Which of the following substances are included as allergens?

Allergy is defined as ..........

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Assertion : Mast cells in the human body release excessive amounts of inflammatory chemicals,which cause allergic reactions.Reason : Allergens in the environment on reaching human body stimulate mast cells in certain individuals.