Assertion: Phenylketonuria is a recessive her | vedclass

Name: Exam Paper Generator | JEE NEET Paper Generator | Vedclass
Brand: Vedclass
Rating: 5 (35 reviews)

Question

(A) Phenylketonuria $(PKU)$ is an autosomal recessive genetic disorder.It is caused by the deficiency of the enzyme phenylalanine hydroxylase,which is

Vedclass · Accepted Answer

If both Assertion and Reason are correct and the Reason is a correct explanation of the Assertion.

Vedclass · Answer

(A) Phenylketonuria $(PKU)$ is an autosomal recessive genetic disorder.It is caused by the deficiency of the enzyme phenylalanine hydroxylase,which is responsible for converting the amino acid phenylalanine into tyrosine.Due to the lack of this enzyme,phenylalanine accumulates in the body and is converted into phenylpyruvic acid and other derivatives.These derivatives are excreted in the urine,hence the name Phenylketonuria. Therefore,both the Assertion and the Reason are correct,and the Reason explains why the condition is named as such and why the substance appears in the urine.

Assertion: Phenylketonuria is a recessive hereditary disease caused by the body's failure to oxidize the amino acid phenylalanine to tyrosine due to a defective enzyme.
Reason: It results in the presence of phenylalanine acid in urine.

Similar Questions

Identify the genotype of the first generation $(I)$ for an autosomal recessive disorder based on the provided pedigree chart.

$A$ colour-blind man marries the daughter of a colour-blind person. Then in their progeny:

Genes of colour blindness are carried in

Which of the following disorders is an autosomal recessive disorder?

What are both Sickle-cell anemia and Huntington's chorea?

Vedclass Test Series

Exam Paper Generator

Online Exam Module

Assertion: Phenylketonuria is a recessive hereditary disease caused by the body's failure to oxidize the amino acid phenylalanine to tyrosine due to a defective enzyme.Reason: It results in the presence of phenylalanine acid in urine.