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(B) The replica plating experiment conducted by Esther and Joshua Lederberg demonstrated that antibiotic-resistant mutants in a bacterial population a

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Natural selection theory

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(B) The replica plating experiment conducted by Esther and Joshua Lederberg demonstrated that antibiotic-resistant mutants in a bacterial population arise spontaneously before exposure to the antibiotic. This experiment provided experimental evidence for the pre-existence of mutations,which supports the concept of natural selection as proposed by Darwin. It proved that the environment does not induce mutations but rather selects for the pre-existing ones that are advantageous for survival.

By performing the replica plating experiment,Lederberg supported the

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