Chemiosmotic theory of ATP synthesis in mitoc | vedclass

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(B) The chemiosmotic theory,proposed by Peter Mitchell,explains the mechanism of $ATP$ synthesis in mitochondria and chloroplasts.In mitochondria,the

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$H^+$ gradient

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(B) The chemiosmotic theory,proposed by Peter Mitchell,explains the mechanism of $ATP$ synthesis in mitochondria and chloroplasts.In mitochondria,the electron transport system $(ETS)$ pumps protons ($H^+$ ions) from the mitochondrial matrix into the intermembrane space.This creates a proton gradient (or $H^+$ gradient) across the inner mitochondrial membrane.The potential energy stored in this electrochemical gradient is used by the enzyme $ATP$ synthase to phosphorylate $ADP$ into $ATP$ as protons flow back into the matrix through the $F_0-F_1$ particle.Therefore,the synthesis of $ATP$ is directly dependent on the $H^+$ gradient.

Chemiosmotic theory of $ATP$ synthesis in mitochondrion is based on

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