Choose the correct statement.

Where do the sporozoites,which have entered human blood,go after leaving the blood?

Assertion $A$: $A$ patient suffering from malaria experiences chills and high fever.
Reason $R$: The rupture of red blood cells by the $Plasmodium$ parasite releases a toxic substance called haemozoin into the blood.

Gametogenesis in $Plasmodium$ occurs in:

Vivax and falciparum are types of which pathogenic microorganism?

Which toxic substance is responsible for the symptoms of malaria?