Consider the following molecules : (p) CH_3- | vedclass

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(D) The rate of hydrolysis of carboxylic acid derivatives depends on the leaving group ability of the group attached to the carbonyl carbon. Better le

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$p > q > r > s$

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(D) The rate of hydrolysis of carboxylic acid derivatives depends on the leaving group ability of the group attached to the carbonyl carbon. Better leaving groups make the carbonyl carbon more electrophilic and facilitate the nucleophilic attack by water. The leaving group ability order is $Cl^- > CH_3COO^- > CH_3CH_2O^- > NH_2^-$. Therefore,the rate of hydrolysis follows the order $:$ $(p) \ (acid \ chloride) > (q) \ (anhydride) > (r) \ (ester) > (s) \ (amide)$. Thus,the correct order is $p > q > r > s$.

Consider the following molecules $:$
$(p) \ CH_3-CH_2-COCl$
$(q) \ CH_3-CH_2-CO-O-COCH_3$
$(r) \ CH_3-CH_2-CO-OCH_2-CH_3$
$(s) \ CH_3-CH_2-CONH_2$
The correct order of rate of hydrolysis is $:$

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Consider the following molecules $:$ $(p) \ CH_3-CH_2-COCl$ $(q) \ CH_3-CH_2-CO-O-COCH_3$ $(r) \ CH_3-CH_2-CO-OCH_2-CH_3$ $(s) \ CH_3-CH_2-CONH_2$ The correct order of rate of hydrolysis is $:$