Consider the following statements:
$I.$ Recombinant $DNA$ technology,popularly known as genetic engineering,is a stream of biotechnology which deals with the manipulation of genetic material by man in vitro.
$II.$ $pBR322$ is the first artificial cloning vector developed in $1977$ by Bolivar and Rodriguez from $E. coli$ plasmid.
$III.$ Restriction enzymes belong to a class of enzymes called nucleases.
Which of the statements given above are correct?

• A
  $I$ and $II$
• B
  $I$ and $III$
• C
  $II$ and $III$
• D
  $I, II,$ and $III$