During ventricular diastole,

In humans,the duration of a cardiac cycle is ......... seconds.

The ventricular diastole has a duration of . . . . . . seconds.

The Oxygen-Fick method is used to measure:

What is the end diastolic volume $(EDV)$ of blood in a normal adult heart (in $,ml$)?

$A$: Isovolumetric systole of a normal cardiac cycle is responsible for the opening of semilunar valves causing the blood flow into aortic aorta and pulmonary aorta.
$R$: During isovolumetric systole,intraventricular pressure increases as semilunar and $AV$ valves are closed and ventricles are contracting.