Edward syndrome is on account of .......

  • A
    $45$ chromosomes instead of $46$
  • B
    Presence of three chromosomes on $18^{th}$ pair of autosome
  • C
    Presence of three chromosomes on $21^{st}$ pair of autosome
  • D
    Presence of three pair of sex chromosomes

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Three copies of chromosome-$21$ in a child with Down's syndrome have been analysed using molecular biology technology to detect any possible $DNA$ polymorphism with reference to different alleles located on chromosome-$21$. Results showed that out of $3$ copies,$2$ of the chromosomes of the child contain the same alleles as one of the mother's alleles. Based on this,when did the non-disjunction event most likely occur?

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