The effect of 2,3-DPG on human blood is that: | vedclass

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Question

(B) $2,3-DPG$ $(2,3-diphosphoglycerate)$ is an organic phosphate found in human red blood cells.Its concentration increases in response to low oxygen

Vedclass · Accepted Answer

It decreases the affinity of $O_2$ for haemoglobin.

Vedclass · Answer

(B) $2,3-DPG$ $(2,3-diphosphoglycerate)$ is an organic phosphate found in human red blood cells.Its concentration increases in response to low oxygen levels,such as at high altitudes.$2,3-DPG$ binds to the deoxygenated haemoglobin,which stabilizes the $T$ (tense) state of the molecule.This binding decreases the affinity of haemoglobin for $O_2$,thereby shifting the oxygen-haemoglobin dissociation curve to the right.This mechanism facilitates the unloading of $O_2$ from the blood to the peripheral tissues where it is needed most.

The effect of $2,3-DPG$ on human blood is that:

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