The end product (C) of the reaction is: | vedclass

Name: Exam Paper Generator | JEE NEET Paper Generator | Vedclass
Brand: Vedclass
Rating: 5 (35 reviews)

Question

(B) $1$. The starting material is ethyl acetoacetate,which contains both a ketone and an ester functional group. $2$. The first step involves the reac

Vedclass · Accepted Answer

Vedclass · Answer

(B) $1$. The starting material is ethyl acetoacetate,which contains both a ketone and an ester functional group. $2$. The first step involves the reaction with ethylene glycol in the presence of an acid catalyst $(H^+)$. Since ketones are more reactive towards nucleophilic addition than esters,the ketone group is selectively protected as a cyclic acetal. $3$. The second step involves the reaction with $2$ equivalents of $PhMgBr$ (a Grignard reagent). The Grignard reagent attacks the ester group,leading to the formation of a tertiary alcohol after the addition of two phenyl groups. $4$. The final step is the acid-catalyzed hydrolysis $(H_3O^+)$,which deprotects the cyclic acetal back to the ketone. $5$. The final product $(C)$ is $CH_3COCH_2C(OH)(Ph)_2$.

The end product $(C)$ of the reaction is:

Similar Questions

When $(X)$ reacts with $(Y)$ in the presence of dilute $(Z)$ solution,$3-$hydroxybutanal is formed. What are $(X), (Y),$ and $(Z)$?

What is the product formed when propanal reacts with dilute sodium hydroxide?

The total number of structural products formed in the following reaction sequence is $CH_3COCl \xrightarrow{i) (CH_3)_2Cd} (P)$; $(P) + CH_3CHO \xrightarrow{ii) NaOH (aq.), \Delta} ?$

Explain the aldol condensation reaction.

Which of the following on reaction with Grignard reagent followed by hydrolysis forms a tertiary alcohol?

Vedclass Test Series

Exam Paper Generator

Online Exam Module