'Exophthalmic goitre' $(Grave's\,disease)$ is caused due to

The highest concentration of iodine is found in the .....

Which of the following absorbs iodine from blood?

Assertion: Hormone calcitonin has an antagonistic effect to that of parathormone.
Reason: Calcitonin decreases blood calcium level while parathormone increases blood calcium level.

What is the effect of $Thyroxine$ on the metabolic rate?

Which of the following are $NOT$ under the control of thyroid hormone?
$A$. Maintenance of water and electrolyte balance
$B$. Regulation of basal metabolic rate
$C$. Normal rhythm of sleep-wake cycle
$D$. Development of immune system
$E$. Support the process of RBCs formation
Choose the correct answer from the options given below: