Explain: Acetylation.

Vedclass pdf generator app on play store
Vedclass iOS app on app store
(N/A) Acetylation is a specific type of acylation reaction where an acetyl group $(CH_3CO-)$ is introduced into an organic compound,typically an amine or alcohol.
In the context of amines,aliphatic and aromatic primary and secondary amines react with acetylating agents like acetyl chloride $(CH_3COCl)$ or acetic anhydride $((CH_3CO)_2O)$ via a nucleophilic substitution reaction to form $N$-substituted amides.
The reaction is generally carried out in the presence of a base,such as pyridine,which acts as an acid scavenger to remove the $HCl$ formed,thereby shifting the equilibrium to the right.
Example of acetylation of ethanamine:
$C_2H_5NH_2 + CH_3COCl \xrightarrow{\text{Pyridine}} C_2H_5NHCOCH_3 + HCl$
(Ethanamine + Acetyl chloride $\rightarrow$ $N$-Ethylethanamide + $HCl$)

Explore More

Similar Questions

$A$ student performed an analysis of an aliphatic organic compound '$X$' which, upon analysis, gave $C=61.01\%$, $H=15.25\%$, $N=23.74\%$. This compound, on treatment with $HNO_2/H_2O$, produced another compound '$Y$' which did not contain any nitrogen atom. However, the compound '$Y$' upon controlled oxidation produced another compound '$Z$' that responded to the iodoform test. The structure of '$X$' is:

The amine $A$,when treated with nitrous acid,gives a yellow oily substance. The amine $A$ is

$Benzamide$ $\xrightarrow{Br_2 / NaOH} X$ $\xrightarrow[\text{alc. } KOH]{CHCl_3} Y$
The conversion of $X$ to $Y$ is

Arrange the following amines in the order of increasing basicity.

In the given chemical reaction $CH_3CH_2NH_2 + CHCl_3 + 3KOH \rightarrow X + Y + 3H_2O$,what are $X$ and $Y$ respectively?

Vedclass Products

For Students

Vedclass Test Series

Mock tests in real JEE/NEET style with performance analysis. 5-day free trial.

Start Free Trial
For Teachers

Exam Paper Generator

Generate Set A/B/C/D exam papers from 7.5L+ questions in 2 minutes. 3 chapters free.

Try Free
For Institutes

Online Exam Module

Live online exams with unlimited students, 360° analytics & white-label branding.

See Demo