Explain the following statement by giving two examples: 'It is not necessary that the pathogen affects an organ or tissue depending upon its point of entry.'

(N/A) The statement implies that the site of infection is not always determined by the entry point of the pathogen. Pathogens often travel through the body to reach specific target organs.
Examples:
$(a)$ $AIDS$ causing virus: Enters through sexual contact or blood transfusion,but spreads to lymph nodes throughout the body.
$(b)$ Japanese encephalitis: The virus enters the blood through a mosquito bite but specifically targets and reaches the brain.
$(c)$ Malaria: The protozoan $Plasmodium$ enters the blood through a mosquito bite,travels to the liver,and then infects the $RBCs$ (Red Blood Cells).