Frame shift mutation occurs when

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(A) frame shift mutation occurs when the addition or deletion of one or more nucleotide bases in a $DNA$ sequence causes a shift in the reading frame

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base is deleted or added.

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(A) frame shift mutation occurs when the addition or deletion of one or more nucleotide bases in a $DNA$ sequence causes a shift in the reading frame of the genetic code. Since the genetic code is read in triplets (codons),changing the number of bases by a value not divisible by $3$ alters the entire sequence of amino acids downstream from the mutation site.

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