Identification and binding of RNA polymerase | vedclass

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(B) In prokaryotic transcription,the $RNA$ polymerase enzyme consists of a core enzyme (composed of subunits $\alpha_2, \beta, \beta', \omega$) and a

Vedclass · Accepted Answer

Sigma factor

Vedclass · Answer

(B) In prokaryotic transcription,the $RNA$ polymerase enzyme consists of a core enzyme (composed of subunits $\alpha_2, \beta, \beta', \omega$) and a sigma $(\sigma)$ factor.The core enzyme is capable of catalyzing the polymerization of ribonucleotides into $RNA$ but lacks the specificity to initiate transcription at the correct site.The sigma $(\sigma)$ factor is responsible for the recognition of the promoter sequence on the $DNA$ template.Once the $RNA$ polymerase holoenzyme (core enzyme + $\sigma$ factor) binds to the promoter,the $\sigma$ factor facilitates the initiation of transcription and is subsequently released.Therefore,the identification and binding of $RNA$ polymerase to the promoter is the function of the sigma factor.

Identification and binding of $RNA$ polymerase to the promoter sequence is a function of

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