In human kidneys,which substances are mainly | vedclass

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(B) The osmolarity gradient in the medullary interstitial fluid of the human kidney is primarily maintained by two substances: $NaCl$ and urea.$NaCl$

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$NaCl$ and urea

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(B) The osmolarity gradient in the medullary interstitial fluid of the human kidney is primarily maintained by two substances: $NaCl$ and urea.$NaCl$ is transported by the ascending limb of the loop of Henle,which is exchanged with the descending limb of the vasa recta.Urea is transported back to the interstitium by the collecting duct.This mechanism,known as the counter-current mechanism,helps in concentrating the urine.

In human kidneys,which substances are mainly responsible for creating the osmolarity gradient of the medullary interstitial fluid?

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