List the disadvantages of insulin obtained from the pancreas of slaughtered cows and pigs.

(N/A) $(i)$ Insulin,being a hormone,is produced in very small amounts in the body. Hence,many animals need to be slaughtered to obtain even small quantities of insulin,making the cost very high due to the demand being much higher than the supply.
$(ii)$ The slaughtering of animals for medical purposes is considered unethical by many.
$(iii)$ There is a potential for an immune response in humans against the administered animal-derived insulin.
$(iv)$ There is a possibility that the slaughtered animals may be infested with infectious microorganisms,which could contaminate the insulin.
$(v)$ This type of insulin may cause allergic reactions in some patients.