Describe the life cycle of $Plasmodium$.

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(N/A) $Plasmodium$ enters the human body as $sporozoites$ (the infectious form) through the bite of an infected female $Anopheles$ mosquito.
The parasites initially multiply within the liver cells and then attack the red blood cells $(RBCs)$.
The $haem$ part of $haemoglobin$ is converted into $haemozoin$,and the $globin$ part becomes food for the parasite.
The $RBCs$ rupture due to the release of the toxic substance $haemozoin$,which is responsible for the chills and high fever recurring every $3-4$ days.
When a female $Anopheles$ mosquito bites an infected person,these parasites enter the mosquito's body and undergo further development.
They multiply within the mosquito's body to form $sporozoites$ that are stored in the salivary glands.
When these mosquitoes bite a human,the $sporozoites$ are introduced into his/her body,thereby initiating the cycle again.
The malarial parasite requires two hosts—humans and mosquitoes—to complete its life cycle.

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