Nobel prize winner $E.W. Sutherland$ demonstrated:

Which of the following hormones bind with intracellular receptors?

Chemically,hormones are divided into which groups?

$A$ molecule that binds to a receptor and induces post-receptor events in a cell is called ...$A$... and a molecule that binds to the receptor and inhibits all post-receptor events is called ...$B$....

Match the following columns:

Column-$I$	Column-$II$
$P$. Peptide, polypeptide, protein hormones	$I$. Epinephrine
$Q$. Steroids	$II$. Thyroid hormones
$R$. Iodothyronines	$III$. Cortisol, testosterone, estradiol, progesterone
$S$. Amino acid derivatives	$IV$. Hormones of pancreas, pituitary, and hypothalamus

Which one of the following flows directly into blood from the seat of its production to act on an organ away from it?