Plasma cells are derived from

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(C) Plasma cells are specialized effector cells of the immune system that secrete large quantities of antibodies. They are differentiated from activat

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$B$-lymphocytes

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(C) Plasma cells are specialized effector cells of the immune system that secrete large quantities of antibodies. They are differentiated from activated $B$-lymphocytes ($B$-cells) upon exposure to an antigen. When a $B$-cell encounters its specific antigen and receives signals from helper $T$-cells,it undergoes clonal expansion and differentiates into plasma cells and memory $B$-cells. Therefore,plasma cells are derived from $B$-lymphocytes.

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