Study the following statements:
$(a)$ The substrate binds to the active site of the enzyme.
$(b)$ Enzymes isolated from thermophilic organisms get denatured at $50^{\circ}C$.
$(c)$ The active site of the enzyme breaks the chemical bonds of the product.
$(d)$ Prosthetic groups are tightly bound to the apoenzyme.
Select the option which includes all correct statements:

• A
  $(a)$ and $(c)$
• B
  $(c)$ and $(d)$
• C
  $(b)$ and $(c)$
• D
  $(a)$ and $(d)$