The S-enantiomer of ibuprofen is responsible | vedclass

Name: Exam Paper Generator | JEE NEET Paper Generator | Vedclass
Brand: Vedclass
Rating: 5 (35 reviews)

Question

(A) To determine the $(S)$-configuration of ibuprofen,we assign priorities to the groups attached to the chiral carbon atom using the Cahn-Ingold-Prel

Vedclass · Accepted Answer

Vedclass · Answer

(A) To determine the $(S)$-configuration of ibuprofen,we assign priorities to the groups attached to the chiral carbon atom using the Cahn-Ingold-Prelog $(CIP)$ sequence rules: $1$. $-COOH$ group (priority $a=1$) $2$. Phenyl group (priority $b=2$) $3$. $-CH_3$ group (priority $c=3$) $4$. $-H$ atom (priority $d=4$) For the $(S)$-configuration,when the lowest priority group $(d=4)$ is pointing away from the viewer (on a dashed bond),the sequence from priority $1$ $\rightarrow 2$ $\rightarrow 3$ must be counter-clockwise. In structure $A$,the $-H$ atom is on a solid wedge (pointing towards the viewer). If we look at the sequence $1$ $\rightarrow 2$ $\rightarrow 3$,it appears clockwise,but because the lowest priority group is towards us,the actual configuration is $(S)$. Alternatively,looking at the provided solution image,the structure shows the $-COOH$ group as priority $a$,the phenyl group as $b$,the $-CH_3$ group as $c$,and the $-H$ atom as $d$ on a dashed bond. The path $a$ $\rightarrow b$ $\rightarrow c$ is counter-clockwise,confirming the $(S)$-configuration.

The $S$-enantiomer of ibuprofen is responsible for its pain-relieving properties. Which one of the following structures shown below is $(S)$-ibuprofen?

Similar Questions

Calculate the total number of stereoisomers for the given molecule,considering the alkene configuration is fixed as trans.

Which of the following compounds is optically inactive?

The number of all the possible stereoisomers formed by the given compound is

Determine the absolute configuration of the given molecule:

The number of stereoisomers for $2-$chloro$-4-$methylhex$-2-$ene is .............

Vedclass Test Series

Exam Paper Generator

Online Exam Module