The major product in the following reaction s | vedclass

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Question

(A) The reaction proceeds as follows:$(i)$ Phenol reacts with $NaOH$ and $CH_3I$ to form anisole (methoxybenzene) via Williamson ether synthesis.(ii)

Vedclass · Accepted Answer

$1-$($4$-methoxyphenyl)propan$-1-$ol

Vedclass · Answer

(A) The reaction proceeds as follows:$(i)$ Phenol reacts with $NaOH$ and $CH_3I$ to form anisole (methoxybenzene) via Williamson ether synthesis.(ii) Anisole undergoes Friedel-Crafts acylation with propionyl chloride $(CH_3CH_2COCl)$ in the presence of anhydrous $AlCl_3$. Since the $-OCH_3$ group is ortho/para-directing,and the para-position is sterically less hindered,the major product is $p$-methoxypropiophenone.(iii) Reduction of the ketone group with $NaBH_4$ yields the corresponding secondary alcohol,$1$-($4$-methoxyphenyl)propan$-1-$ol.Therefore,the correct option is $A$.

The major product in the following reaction sequence is:

Similar Questions

Write the chemical reactions for the following conversions:
$1.$ Phenol to Anisole and Phenetole
$2.$ Chlorobenzene to $p$-Bromoanisole

Give equations of the following reactions:
$(i)$ Oxidation of propan$-1-$ol with alkaline $KMnO_4$ solution.
$(ii)$ Bromine in $CS_2$ with phenol.
$(iii)$ Dilute $HNO_3$ with phenol.
$(iv)$ Treating phenol with chloroform in presence of aqueous $NaOH$.

Identify the major product.

Which of the following substances releases hydrogen gas upon reacting with $Na$ metal?

List-$I$ contains reactions and List-$II$ contains major products. Match each reaction in List-$I$ with one or more products in List-$II$ and choose the correct option.

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