The relative reactivities of acyl compounds towards nucleophilic substitution are in the order of

  • A
    $Acid \ anhydride > Amide > Ester > Acyl \ chloride$
  • B
    $Acyl \ chloride > Ester > Acid \ anhydride > Amide$
  • C
    $Acyl \ chloride > Acid \ anhydride > Ester > Amide$
  • D
    $Ester > Acyl \ chloride > Amide > Acid \ anhydride$

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