The total number of negative charges in the t | vedclass

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Question

(A) At $pH$ $12.5$,which is a highly basic medium,all acidic groups in the tetrapeptide $Gly-Glu-Asp-Tyr$ will be deprotonated.$1$. The $C$-terminal $

Vedclass · Accepted Answer

$4$

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(A) At $pH$ $12.5$,which is a highly basic medium,all acidic groups in the tetrapeptide $Gly-Glu-Asp-Tyr$ will be deprotonated.$1$. The $C$-terminal $-COOH$ group becomes $-COO^-$.$2$. The side chain $-COOH$ of $Glu$ becomes $-COO^-$.$3$. The side chain $-COOH$ of $Asp$ becomes $-COO^-$.$4$. The phenolic $-OH$ group of $Tyr$ becomes $-O^-$.Therefore,the total number of negative charges is $4$.

The total number of negative charges in the tetrapeptide,$Gly-Glu-Asp-Tyr$,at $pH$ $12.5$ will be $......$ .

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