What will happen if the secretion of parietal | vedclass

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(A) The parietal cells (also known as oxyntic cells) of the gastric glands secrete $HCl$ (hydrochloric acid).In the presence of $HCl$,pepsinogen (a pr

Vedclass · Accepted Answer

In the absence of $HCl$ secretion,inactive pepsinogen is not converted into the active enzyme pepsin.

Vedclass · Answer

(A) The parietal cells (also known as oxyntic cells) of the gastric glands secrete $HCl$ (hydrochloric acid).In the presence of $HCl$,pepsinogen (a proenzyme),which is an inactive precursor of the enzyme pepsin,is converted into its active form,$i.e.$,pepsin.The activated pepsin then acts through autocatalysis to convert more pepsinogen into pepsin.This pepsin enzyme is the primary protease or proteolytic enzyme of the stomach.$	ext{Pepsinogen (Inactive form)} \xrightarrow{HCl} 	ext{Pepsin (Active form)}$Therefore,if the secretion of $HCl$ is blocked,inactive pepsinogen will not be converted into the active enzyme pepsin.

What will happen if the secretion of parietal cells of gastric glands is blocked with an inhibitor?

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