Which of the following acts as a second messenger?

Given below are two statements.
Statement $I$: Mode of action of catecholamines,peptide and polypeptide hormones is through cell membrane receptors.
Statement $II$: These hormones are non-steroid,water soluble and lipid insoluble hormones.
In the light of above statements,choose the correct option from below:

Receptors are made up of $.......$.

Given below are two statements: one is labelled as Assertion $(A)$ and the other is labelled as Reason $(R)$.
Assertion $(A)$: $FSH$,which interacts with membrane-bound receptors,does not enter the target cell.
Reason $(R)$: Binding of $FSH$ to its receptors generates a second messenger (cyclic $AMP$) for its biochemical and physiological responses.
In the light of the above statements,choose the most appropriate answer from the options given below:

Identify $A, B$ and $C$ in the diagrammatic representation of the mechanism of hormone action.
Select the correct option from the following:

Which of the following statements are applicable to hormones?
$I -$ Neural messengers
$II -$ Intercellular messengers
$III -$ Produced in trace amounts
$IV -$ Nutrient chemicals
$V -$ Released into the blood after production.